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P.S. You Should Know... | Issue #157

👋 Welcome back to P.S. You Should Know… probably the best newsletter published on Sundays between 6-7
March 29 · Issue #157 · View online
P.S. You Should Know...
👋 Welcome back to P.S. You Should Know… probably the best newsletter published on Sundays between 6-7am CST, and definitely the best one published by me. Now in its fourth year!

my story 🚀
Some entrepreneurs are concerned that continuing their efforts at sales and marketing will look “out of touch” or “tone deaf” given the circumstances. While valid in some cases, I think the concept is oversold. The crisis has taken a significant portion of our collective mindshare. Judging by my inbox and every website I’ve visited this week, it’s on track to take more than its fair share. Remember, we’re prone to overweight the importance of the topics we encounter most often. While we act for the benefit of public health, we should remember that most of the public remains healthy and has great cause for optimism. While we band together distantly, remember that we will get through this together. The way forward is not business as usual, but it is business. Trade brings people together and creates prosperity. Adapt your business plan, yes, but don’t stop trying to grow right now.
someone else's words 💬
fun facts 🙌
Massive earthquakes, risk aversion, and entrepreneurship. Researchers in Italy have found that early exposure to a massive earthquake makes people significantly more risk averse, negatively impacting the rates of entrepreneurship over time. | learn more
Buying under the influence (of a frenzy). “The Securities and Exchange Commission suspended trading of Zoom Technologies on Thursday, partly because investors are confusing it with Zoom Video, which has seen a surge share price due to COVID-19. It will resume trading April 9.” | learn more
25,000-year-old building made of 60 mammoths. “Archaeologists find structure in what is now Russia that dates back 25,000 years made of the bones of 60 mammoths.” | learn more
oh, chicago 🏆
📷 Laura Hedien, Storm Clouds Photography
📷 Laura Hedien, Storm Clouds Photography
Photos of a deserted Chicago. “The deserted city of Chicago the afternoon of the lock-down March 21, 2020.” | learn more
‘Where’s Lightfoot’ on Instagram. A fun new game on the internet. | learn more
These Chicago startups are hiring right now. This is great! From Josh Inglis, founder of marketing agency Propllr: “I’ve been reaching out to Chicago startups to see who is hiring – not just to see who has a careers page up, but to learn who is actively looking for candidates right now.” | learn more
tech, startups, internet ⚡
Pricing determines your business. This is a great article about how price drives business model decisions. “Price is not an exercise in maximizing some micro-economic supply/demand curve, slapped post-facto onto the product. Rather, it fundamentally determines the nature of the product and the structure of the business that produces it.” | learn more
Founders, extend your cash runway by taking these steps right now. It’s been a long time since belt-tightening was in vogue. Now that we’re on the road to austere times, I’m seeing helpful articles about how to control costs. This guide is aimed at SaaS startups with a cash burn, but the advice is more broadly applicable. | learn more
better doing 🎯
Happiness is peace in motion. Naval Ravikant has transitioned from startup investor to philosopher, and I like it! “The first problem with attaining peace is that no activity will get you there. Fundamentally, peace is inactivity; it’s a sense that everything is fine.” | learn more
Communicating online. Seth Godin highlights four ‘big leaps’ that exist when moving communication online. “It’s not just like the real world but with keyboards.” | learn more
to your health ⚕
Senators who led pharma-friendly reform get pharma cash. “Three senators on a revived subcommittee received more than $100,000 each from drugmakers.” | learn more
retail therapy 💸
Retail and e-tail metrics in post-virus world. There’s a chance of sampling bias here, but the trends are fascinating anyway. Luxury sector conversion rates are up a surprising 35-40% vs benchmark. “[Marketing agency] WITHIN … tracking year-over-year trends in ecommerce revenue, ad spend, and conversion rate relative to the pre-COVID benchmark period.” | learn more
10 ecommerce trends shaping the future of DTC in 2020. There are some interesting concepts noted here, including “LTV Is Everything, LTV Is Nothing: Meet Your Cash Multiplier.” I also am fond of the notice at the top: “This article was written a week prior to the coronavirus pandemic.” | learn more
under the microscope 🔬
A molecular model of the artificial antibody system. The nanosheet is shown in green, and the loopoids in purple. The larger structure looming over it is an anthrax protein
A molecular model of the artificial antibody system. The nanosheet is shown in green, and the loopoids in purple. The larger structure looming over it is an anthrax protein
Faster testing for artificial antibodies. Researchers at Berkeley have created a new system to rapidly test artificial antibodies. This feels like a strong brute-force attack against pathogens. “The system starts with a nanosheet made up of molecules called peptoids. This is then coated in loops of other peptoids, which the team calls “loopoids.” The nanosheet provides the supporting structure, while the loopoids are the active parts, latching onto molecules that may be present in different pathogens.” | learn more
Bacteria farms produce protein that clears fat from bloodstream. As always, this is very early research not yet applied to humans. “Triglycerides are a form of fat that circulates through the bloodstream, and high levels can lead to obesity and related illnesses. Now, researchers have found a way to efficiently produce a protein that clears these fats from the bloodstream.” | learn more
thoughts of food 🍔
Cheesecake Factory tells landlords not to hold their breath for April rent check. It turns out that the lease obligations take a large haircut in bankruptcy court, creating a strong incentive for landlords to sit there and take the pain. | learn more
Lab-grown chicken nuggets are coming. Nature’s Fynd, a Chicago startup formerly known as Sustainable Bioproducts, raised $80 million to produce lab-grown protein products using a fermentation process. | learn more
on the blockchain ⛓
Black Thursday for MakerDAO: $8.32 million was liquidated for $0. About $8 million was withdrawn from the stablecoin system on March 12th and 13th. “This problem arose not because of a sharp drop in price and the lack of collateral, but due to manipulations of initiative keepers (liquidators).” | learn more
calls to action 👇
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