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P.S. You Should Know... | Issue #241

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November 7 · Issue #241 · View online
P.S. You Should Know...
👋 Welcome back to P.S. You Should Know… probably the best newsletter published on Sundays between 6-7am CST, and definitely the best one published by me. Now in its fifth year!

my story 🚀
Fairy Princesses 🧚‍♀️👸
Fairy Princesses 🧚‍♀️👸
someone else's words 💬
  1. Don’t be fooled by crypto. Crypto is mainstream now and the future is here, right? Not quite yet. I tried to buy an NFT on the most popular marketplace with the most popular wallet and after about 90 minutes of fumbling around I finally failed. “No keyring found for the requested account. Error info: There are no keyrings; There are keyrings, but none match the address;” What does that mean? I have no idea. But after $200+ of fees in the form of digital gas, I decided to save myself the next $130 in fees and just give up. While I remain a long-term believer and enthusiast, this was a healthy reminder that we’re at least one more “crypto winter” away from a reliably good experience.
  2. But don’t write off crypto. I was reminded this week of a startup I declined to invest in. It was 2017 and they hadn’t launched a product yet. In 2019, I finally tried their product and it sucked. Now the product doesn’t suck anymore. In July of this year they were valued at $1.6 billion. Oops. The lesson? Things can get better when people keep working at them. Crypto has a lot of smart people working to make it better. I believe it’s going to get a lot better.
fun facts 🙌
This word does not exist. Machine learning and fake words. | learn more
The Financial Times has jokes. Check out their “page not found” page. | learn more
Ransomware gang drama. “When ransomware group REvil reappeared in September after a nearly two-month downtime, its return was met with a less-than-friendly reception on the cybercriminal underground.” | learn more
tech, startups, internet ⚡
Eye-scanning silver orb cryptocurrency. “Over the summer, the world learned that tech investor Sam Altman was plotting to co-found a new startup that struck many as dystopian, albeit light on details: a cryptocurrency called Worldcoin that is distributed by scanning people’s eyeballs with an inscrutable silver orb.” | learn more
How to shut down a startup. “Just six weeks earlier, in October 2020, Petal had finalized pricing for manufacturing its germ-freezing trash can, which consumers could use to get rid of germs in their trash and eliminate odors. Then, the cost of manufacturing the product shot up by 275 percent, due to the COVID-19 pandemic and increased demand for refrigeration products to store food and vaccines.” | learn more
Stratechery on Meta. “Meta exists because Zuckerberg believes it needs to exist, and he is devoted to making the metaverse a reality; it’s his call, for better or worse.” | learn more
better doing 🎯
How to get useful answers to your questions. “5 years ago I wrote a post called how to ask good questions. I still really like that post, but it’s missing a few of the tactics I use to get useful answers like “interrupt people when they’re going off on an irrelevant tangent”.” | learn more
retail therapy 💸
Four retail IPOs. Scott Galloway on Warby Parker, Rent the Runway, Allbirds, and the Swiss shoe company On. | learn more
under the microscope 🔬
Why do placebos work? Scientists used fMRI to detect which parts of the brain were pathways for the placebo and nocebo effects. They found the brainstem active during both. | learn more
New version of brain stimulation treats severe depression in 5 days. This modified version of transcranial magnetic stimulation had a success rate of 78% vs 30%, and takes 5 days vs 6 weeks. | learn more
The secret lives of cells — as never seen before. An approachable deep dive into cutting-edge microscopy. I find the state of the art incredibly impressive yet clearly lacking. For example, “The best-kept secret of tomography is that when you look at a mammalian cell, a tomograph is less than 0.1% of that cell.” | learn more
big ideas 📚
Helion secures $2.2B to commercialize fusion energy. “Helion, as a company, has been focusing less on fusion as a science experiment and more on a more important question: Can their technology generate electricity at a commercial and industrial scale?” | learn more
Turning ordinary cells into human eggs. “A few years ago, a young man from California’s technology scene began popping up in the world’s leading developmental biology labs. These labs were deciphering the secrets of embryos and had a particular interest in how eggs are formed. Some thought if they discovered that recipe, they would be able to copy it and transmute any cell into an egg.” | learn more
on the blockchain ⛓
Centralized exchange NFT platforms. Exchanges, including Coinbase and FX, are getting into the NFT trading business. Messari highlights their advantages and disadvantages compare to decentralized platforms. | learn more
calls to action 👇
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