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P.S. You Should Know... | Issue #247

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December 19 · Issue #247 · View online
P.S. You Should Know...
👋 Welcome back to P.S. You Should Know… probably the best newsletter published on Sundays between 6-7am CST, and definitely the best one published by me. Now in its fifth year!

my story 🚀
Happy birthday Petra! 🦄
Happy birthday Petra! 🦄
fun facts 🙌
The list of potentially popular deregulation ideas. Not without controversy. | learn more
A romance novelist desperately tries to romanticize midwestern winter. “Her eyes said it all, which was convenient because he couldn’t hear anything through his earmuffs.” | learn more
Why retaining walls collapse. “When you see a retaining wall in the wild, the job of holding back soil looks effortless. But that’s usually only true because much of the wall’s structure is hidden from view. A retaining wall is essentially a dam, except instead of water, it holds back earth.” | learn more
tech, startups, internet ⚡
How TikTok reads your mind. The New York Times explains, based on an internal document. “The document, headed “TikTok Algo 101,” was produced by TikTok’s engineering team in Beijing. A company spokeswoman, Hilary McQuaide, confirmed its authenticity, and said it was written to explain to nontechnical employees how the algorithm works.” | learn more
NewLimit: a company built to extend human healthspan. Coinbase founder Brian Armstrong and venture capitalist Blake Byers are starting a new company. “NewLimit will start by deeply interrogating epigenetic drivers of aging and developing products that can regenerate tissues to treat specific patient populations.” | learn more
The future holds a lot of potential, but make sure you don’t overpay for it. An entertaining set of stock charts. But also, to state the counter-argument, any one of these could pan out asymmetrically (let’s say, 100x), making the losers irrelevant. | learn more
better doing 🎯
What is an anti-mentor? This is a short clip from The Knowledge Project where William Irvine explains the benefits of having an anti-mentor, “someone who, when they look down on you or disagree with you, you know you’re doing something right.” | learn more
It’s hard to leave a tool that worked for you. A short perspective on making the leap from conserving cash at all costs to using cash at all costs. | learn more
to your health ⚕
In NYC, the future of healthtech Is female. “New York digital health companies created by and for women hit new heights this year, placing this city at the center of the burgeoning femtech space.” | learn more
Blood draws from the comfort of home. “Patients simply stick the button device, which is roughly the size of a ping pong ball, on their arm with a light adhesive and press the device’s large red button, which causes a vacuum to form. A lancet in the device pricks the surface of the skin and the vacuum draws blood out of the capillaries and into a sample pod at the bottom of the device.” | learn more
retail therapy 💸
The Amazon empire strikes back. Stratechery: “Amazon’s owning the end to end supply chain makes it harder for merchants to ditch Amazon. Because the alternative logistics network form China are more expensive and more prone to failures. Investment years ago creates value and loyalty today.” | learn more
under the microscope 🔬
Mitochondria discovery reveals a plant extract that could combat obesity. “The study carried out at the University of Hong Kong sought to dig into the reasons why fat metabolism works at a slower rate in obese patients. Scientists suspect this is the result of abnormally functioning mitochondria, the cell’s powerhouses that turn nutrients into energy…” | learn more
thoughts of food 🍔
How a cream cheese shortage is affecting N.Y.C. bagel shops. Oy vey! “Supply chain problems that have hit businesses across the country now threaten a quintessential New York treat.” We don’t have this problem in Austin, mostly because there’s (oddly) almost no demand for bagels. | learn more
We eat at the worst Michelin starred restaurant, ever. This is a scathing review of a dining experience at Bros. restaurant in Italy. “There is something to be said about a truly disastrous meal, a meal forever indelible in your memory because it’s so uniquely bad, it can only be deemed an achievement.” | learn more
on the blockchain ⛓
Michael Jordan jumps into web3. “The NBA legend and son Jeffrey Jordan are launching HEIR, a fan engagement platform built on the Solana blockchain.” | learn more
calls to action 👇
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