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P.S. You Should Know... | Issue #265

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April 24 · Issue #265 · View online
P.S. You Should Know...
👋 Welcome back to P.S. You Should Know… probably the best newsletter published on Sundays between 6-7am CST, and definitely the best one published by me. Now in its sixth year!

my story 🚀
Nice to see so many friends again at the Economic Club of Chicago!
Nice to see so many friends again at the Economic Club of Chicago!
fun facts 🙌
PFA: An acronym you’ll need to google to understand. Someone used this in an email to a friend and all of us were stumped. | learn more
How I raised queen bees. From this video, I learned that matching a queen to a hive is a game of trial & error. | learn more
Is it true the Eiffel Tower is taller in the summer? Yes, “[and] the tower is likely to lean due to the unequal heating effect on the sunny and shady sides.” | learn more
tech, startups, internet ⚡
Success and failure at Pebble. The cofounder of the original smart watch, Eric Migicovsky, shares his story. “I’ve been giving a talk on the importance of learning from failure to every YC batch for last few years. I wrote this post in 2017 but never published it. I dusted it off for the 10 year anniversary of Pebble’s launch on Kickstarter.” | learn more
Why VC firms are registering as investment advisors. “I believe that we will continue to see more and more traditional venture capital firms decide to register because their business models will need to evolve as the overall venture capital industry continues to change and competition increases.” | learn more
Metaverse builders see virtual pets as their killer app. “Pokemon Go creator Niantic revealed its next game yesterday, an augmented reality pet simulator named Peridot. … Similar to Pokémon Go, the game uses a phone’s camera to make the creatures visible in an overlay to the real world, using augmented reality techniques.” | learn more
better doing 🎯
How people think. “This article describes 17 of what I think are the most common and influential aspects of how people think. It’s a long post, but each point can be read individually. Skip the ones you don’t agree with and reread the ones you do – that itself is a common way people think.” | learn more
Crony beliefs. Why do we believe crazy things? “Just as money can pervert scientific research, so everyday social incentives have the potential to distort our beliefs.” | learn more
to your health ⚕
New time-restricted eating research. The NYT headline is “Scientists find no benefit to time-restricted eating.” That’s a wildly broad interpretation of the actual study, which was conducted on 139 participants, all of whom were obese, and focused largely on weight loss. | learn more
retail therapy 💸
Ogilvy will no longer work with influencers who edit their bodies or faces for ads. “Ogilvy’s policy comes as the UK government reviews the Digitally Altered Body Image Bill that would require an influencer to disclose edited content.” Since influence transcends geographies, there’s probably some interesting game theory to be considered here. | learn more
under the microscope 🔬
New technique kills tumors with sound waves. This is an incredible development and it’s already in human trials. “The new treatment is called "histotripsy,” and it noninvasively directs ultrasound waves so that the target tissue is mechanically destroyed — and with millimeter precision. This novel technique is presently being deployed in a human liver cancer trial in both the U.S. and Europe.“ | learn more
DNA synthesis is the workhorse of modern biotech. Part 2 of the 4-part series I started sharing last week. Former Google CEO Eric Schmidt gave a talk at a biology conference and said that he felt “your industry is at the same stage mine was in 40 years ago when I started my career in tech.“ | learn more
Infrared mind control. “Now, scientists at the Wu Tsai Neurosciences Institute at Stanford University have developed the first non-invasive technique for controlling targeted brain circuits in behaving animals from a distance.” | learn more
calls to action 👇
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