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P.S. You Should Know... | Issue #280

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August 7 · Issue #280 · View online
P.S. You Should Know...
👋 Welcome back to P.S. You Should Know… probably the best newsletter published on Sundays between 6-7am CST, and definitely the best one published by me. Now in its sixth year!

my story 🚀
A great ending to our time in Chicago this summer!
A great ending to our time in Chicago this summer!
fun facts 🙌
Diamonds are forever. “The British financiers who had organized the South African mines quickly realized that their investment was endangered; diamonds had little intrinsic value — and their price depended almost entirely on their scarcity.” And so, the De Beers Consolidated Mines, Ltd. company came into existence to manufacture that scarcity. | learn more
Whale sharks have tiny teeth on their eyeballs. “The scientists also noted that whale sharks have the ability to partially retract their eyeballs into their skulls, reports Hannah Osbourne for Newsweek. Both protective mechanisms—retractability and the tiny teeth—suggest to the researchers that whale shark’s eyes might be more important to the fish’s survival than previously thought.” | learn more
tech, startups, internet ⚡
The end of social media. And the rise of recommendation media which places “far less emphasis on friends and social graphs in favor of carefully curated, magical algorithmic experiences that match the perfect content for the right people at the exact right time.” | learn more
better doing 🎯
What if you never sort your life out? “Are you still under the illusion that you’ll one day reach a point in your life where you no longer have any problems?” | learn more
to your health ⚕
Amazon and One Medical. A deep dive into the recently announced acquisition of “the O.G. tech enabled primary care platform.” One tidbit I was missing is that half of One Medical’s revenue in Q1 2022 came from Medicare. | learn more
Media coverage of “world’s biggest four-day workweek trial.” The pilot is far from concluded, but that doesn’t stop the feel-good stories from coming out. “The six-month pilot commits 3,300 workers across 70 companies to work 80% of their usual week in exchange for promising to maintain 100% of their productivity.” | learn more
under the microscope 🔬
Early Europeans could not tolerate milk but drank it anyway. The NYT reports on this study: “Dr. Evershed and his colleagues found that Europeans were consuming milk without lactase for thousands of years, despite the misery from gas and cramping it might have caused.” | learn more (no paywall on this link)
To fast or to feed? There isn’t any solid research about whether fasting helps the human body fight an infection. But there was a study published Cell in 2016 that found mice fared better against bacteria while fasted, and against viruses while fed — specifically with glucose. | learn more
big ideas 📚
24 charts that show we’re (mostly) living better than our parents. Compared to the 1980s, Americans are eating more fresh fruit and fresh veggies and many products (including cars) are more affordable. “I went through all 1,566 pages of the 1980 Sears catalog to find items I could easily compare with present-day products. Almost every item I looked at saw significant declines in the hours of work required it buy it.” | learn more
AlphaFold reveals the structure of the protein universe. A year after Google’s DeepMind team released AlphaFold, an AI system that can determine the shape of any protein from its sequence, comes this: “[W]e’re now releasing predicted structures for nearly all catalogued proteins known to science, which will expand the AlphaFold DB by over 200x - from nearly 1 million structures to over 200 million structures - with the potential to dramatically increase our understanding of biology.” | learn more
calls to action 👇
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